QuickView for Neutrophil elastase;jsessionid=5DA7252A505008A652470C2A7877DAE1;jsessionid=51FE922A6E9BC04EDF2076B7224019A9 (gene)
- Gene Symbol:
- Elane
Rattus norvegicus - Full name:
- elastase, neutrophil expressed
- Synonyms:
- Ela2, neutrophil elastase, elastase 2, neutrophil
- Genomic Location:
- Chr 7: 11329644-11331467
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
cytokine binding | enzyme binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | serine hydrolase activity | anion binding | transcription corepressor activity | ion binding | heparin binding | protein binding | glycosaminoglycan binding | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | protease binding | transcription coregulator activity | peptidase activity
GO Biological Process
positive regulation of immune response | positive regulation of smooth muscle cell proliferation | response to radiation | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | positive regulation of leukocyte adhesion to vascular endothelial cell | positive regulation of leukocyte tethering or rolling | cell motility | response to lipopolysaccharide | neutrophil mediated killing of bacterium | proteolysis | regulation of localization | defense response to other organism | establishment of localization | regulation of immune system process | negative regulation of cellular process | negative regulation of RNA biosynthetic process | negative regulation of growth of symbiont involved in interaction with host | defense response | killing by host of symbiont cells | positive regulation of cell adhesion | positive regulation of cellular component movement | defense response to Gram-negative bacterium | interaction with symbiont | positive regulation of cellular biosynthetic process | cellular process | regulation of cytokine biosynthetic process | regulation of cell motility | localization | antibacterial peptide production | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | interspecies interaction between organisms | response to yeast | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | regulation of metabolic process | regulation of cellular extravasation | response to UV | response to stimulus | defense response to fungus | peptide biosynthetic process | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | positive regulation of cell-cell adhesion | inflammatory response to antigenic stimulus | positive regulation of cytokine biosynthetic process | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | negative regulation of metabolic process | regulation of cell adhesion | cellular biosynthetic process | leukocyte migration | regulation of nucleic acid-templated transcription | locomotion | antibacterial peptide biosynthetic process | response to light stimulus | response to external biotic stimulus | nitrogen compound metabolic process | regulation of interleukin-8 biosynthetic process | negative regulation of growth | biosynthetic process of antibacterial peptides active against Gram-negative bacteria | neutrophil mediated killing of fungus | cell migration | antibacterial humoral response | leukocyte mediated immunity | regulation of gene expression | cell killing | negative regulation of chemokine production | response to lipid | modification of morphology or physiology of other organism | negative regulation of cytokine production | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of cell migration | transcription corepressor activity | cellular amide metabolic process | vesicle-mediated transport | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell migration | biosynthetic process | regulation of leukocyte migration | positive regulation of cellular extravasation | negative regulation of cytokine biosynthetic process | response to bacterium | response to fungus | regulation of cellular metabolic process | antimicrobial humoral immune response mediated by antimicrobial peptide | humoral immune response | inflammatory response | regulation of protein metabolic process | defense response to bacterium | positive regulation of cell proliferation | peptide metabolic process | regulation of locomotion | regulation of RNA metabolic process | acute inflammatory response to antigenic stimulus | disruption by host of symbiont cells | antimicrobial humoral response | protein metabolic process | regulation of growth | response to organic substance | import into cell | killing of cells of other organism | metabolic process | negative regulation of interleukin-8 biosynthetic process | negative regulation of growth of symbiont in host | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | endocytosis | immune response | leukocyte mediated cytotoxicity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | amide biosynthetic process | positive regulation of leukocyte migration | serine-type endopeptidase activity | serine-type peptidase activity | negative regulation of interleukin-8 production | positive regulation of cytokine production | leukocyte migration involved in inflammatory response | negative regulation of protein metabolic process | regulation of transcription, DNA-templated | endopeptidase activity | regulation of cytokine production | response to biotic stimulus | neutrophil mediated killing of gram-negative bacterium | regulation of chemokine production | negative regulation of transcription by RNA polymerase II | regulation of cell-cell adhesion | neutrophil mediated immunity | transcription coregulator activity | positive regulation of metabolic process | positive regulation of interleukin-8 biosynthetic process | acute inflammatory response | immune system process | cellular metabolic process | peptidase activity | regulation of smooth muscle cell proliferation | positive regulation of cell motility | negative regulation of chemokine biosynthetic process | phagocytosis | positive regulation of leukocyte cell-cell adhesion | response to other organism | macromolecule metabolic process
GO Cellular Component
secretory granule | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | protein-containing complex | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | transcriptional repressor complex | organelle | extracellular space | intracellular vesicle | cell surface | intracellular
